Since late March 2018, thousands of Palestinians have participated in the weekly Great March of Return (GMR) demonstrations in the vicinity of Israel’s perimeter fence between the Gaza Strip and Israel, calling for the Palestinian right of return and the ending of the Israeli blockade. The large number of casualties among unarmed Palestinian protestors, in particular the high number injured by live ammunition -in circumstances that did not appear to constitute an imminent threat of death or serious injury to Israeli soldiers behind the fence, has raised concerns about excessive use of force by Israeli forces. The first article in this month’s Bulletin examines the humanitarian impact of these injuries on the individuals themselves and the implications for the overstretched Gaza health system.